Drug Standards
Medchemexpress LLC Citalopram (hydrobromide) | 59729-32-7 | 99.9% | 100 MG
Citalopram hydrobromide is a selective serotonin reuptake inhibitor (SSRI), with blood-brain barrier permeability. It inhibits 5-HT uptake into synaptosomes and in rabbit blood platelets, exhibiting an antidepressant effect. It also demonstrates concentration-dependent cytotoxicity on the viability of various rat and human neuroblastoma cell lines and human primary Schwann cells.
- Selective serotonin reuptake inhibitor (SSRI)
- Blood-brain barrier permeability
- Inhibits 5-HT uptake
- Antidepressant effect
Apexbio Technology LLC Cimetidine 51481-61-9 10mM (in 1mL DMSO)
Cimetidine is an H2 histamine receptor antagonist displaying partial agonist properties at the histamine H2 receptor (H2R) This compound functions by reversibly inhibiting the binding of histamine to gastric parietal cell receptors thereby suppressing gastric acid secretion In cell-based assays cimetidine exhibits an inhibitory activity toward H2 receptors with reported IC50 values in the micromolar range In biomedical research cimetidine is employed to investigate gastric acid secretion regulation mechanisms and receptor-ligand interactions related to gastrointestinal physiology Further due to its pharmacological characteristics distinct from other H2 antagonists cimetidine is frequently studied as an experimental reagent in oncology studies focusing on gastrointestinal tumor growth modulation and related signaling pathways
Cayman Chemical MetronIdazole ImpurIty G 10mg
A potential impurity found in commercial preparations of metronidazole; an inactive metabolite of metronidazole
Apexbio Technology LLC Itraconazole(Synonyms: Sporanox, Orungal, R51211, Lozanoc, Triasporin, Fungitraxx, Onmel, Itranox, Sporal, Itrizole, Candistat), 200mg, CAS: 84625-61-6.
Itraconazole (CAS 84625-61-6) is a triazole-based antifungal compound that functions primarily by inhibiting cytochrome P450 enzymes particularly CYP3A4 As both a substrate and inhibitor of CYP3A4 itraconazole undergoes oxidative metabolism into hydroxylated keto- and N-dealkylated derivatives all with demonstrated inhibitory activities comparable or superior to the parent compound In addition to antifungal effects itraconazole inhibits the hedgehog signaling pathway and angiogenesis Due to its affinity for mammalian CYP-P450 enzymes itraconazole is frequently employed in drug interaction studies assessing CYP3A-mediated metabolism
Medchemexpress LLC Amoxicillin | 26787-78-0 | 99.9% | 10 G
Amoxicillin is an antibiotic known for its good oral absorption and broad-spectrum antimicrobial activity. It functions by inhibiting the biosynthesis of polypeptides in the bacterial cell wall, which in turn hinders cell growth.
- Possesses good oral absorption
- Provides broad-spectrum antimicrobial activity
- Inhibits bacterial cell wall biosynthesis
- Used in various cellular and in vivo research models
Medchemexpress LLC Linagliptin impurity 11 | 1803079-48-2 | 25mg
Linagliptin impurity 11 (Linagliptin impurity YYJ) is an impurity of Linagliptin (HY-10284)
Sigma Aldrich Fine Chemicals Biosciences Fipronil for system suitability European Pharmacopoeia (EP) Reference Standard | 120068-37-3 | MFCD00867812 |
Fipronil for system suitability European Pharmacopoeia (EP) Reference Standard | Mol Wt: 437.15 | 120068-37-3 | MFCD00867812 |
Medchemexpress LLC Amoxicillin trihydrate mixture with potassium clavulanate (4:1) | 100 MG
Amoxicillin trihydrate mixture with potassium clavulanate (4:1) is an antibiotic with good oral absorption and broad-spectrum antimicrobial activity. It functions by inhibiting the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth.
- Decreases living cells and increases the degree of cell wall rupture in L. acidophilus in a dose-dependent manner
- Inhibits bacterial numbers and improves survival rate in female ICR/Swiss mice infected with organisms having MICs of 1 mg/L or less
- Shows activity against infection with Chlamydia trachomatis in swiss albino mice
Medchemexpress LLC Isosorbide | 652-67-5 | 98.8% | 500 G
Isosorbide is an orally active vasodilating agent used in the research of heart failure and angina (chest pain). It also acts as an oral hyperosmotic diuretic.
- Orally active vasodilating agent
- Used for research of heart failure and angina (chest pain)
- Oral hyperosmotic diuretic
- Appearance: solid, white to off-white
- Molecular weight: 146.14
- Formula: C6H10O4
- Soluble in H2O and DMSO
Cayman Chemical D-a-Tocopheryl QuInon 100mg
An oxidative metabolite of vitamin E; has antioxidant activity in ORAC and radical trapping assays at 25 µM; inhibits (1S,3R)-RSL3-induced ferroptosis in Q7 cells (EC50 = 0.233 µM); decreases serum MDA and blood glucose levels and restores the number and diversity of intestinal microflora in a rat model of high cholesterol and cholate diet-induced NASH at 20 mg/kg
Medchemexpress LLC Methylprednisolone succinate | 2921-57-5 | MFCD00271782 | 99.7% | 474.5 g·mol-1 | C26H34O8 | 10 MG
Methylprednisolone succinate is a synthetic glucocorticoid research standard (prodrug of methylprednisolone) used as an anti-inflammatory reference in analytical and method-development applications. Supplied as a white to off-white solid for laboratory use; not for human or clinical use.
- Purity 99.73%.
- CAS number 2921-57-5.
- Molecular weight 474.5 g·mol-1.
- Available in small research sizes, including 10 mg.
- COA and SDS available; store per COA instructions.
- For research use only; not for human use.
Sigma Aldrich Fine Chemicals Biosciences Cidofovir Related Compound A United States Pharmacopeia (USP) Reference Standard | 1312776-50-3 | 15MG
Cidofovir Related Compound A United States Pharmacopeia (USP) Reference Standard | Mol Wt: 307.24 | 1312776-50-3 | 15MG
Sigma Aldrich Fine Chemicals Biosciences Amitriptyline N-AY-D-glucu
A certified SOLUTIONon standard of Amitriptyline N-AY-D-glucuronide a metabolite of the tricyclic antidepressant amitriptyline. Sold under trade names such as Amitrip Elavil and Levate amitriptyline is prescribed to treat a number of mental disorders ranging from major depressive disorder and anxiety disorder to bipolar disorder. This SOLUTIONon-based Certified Reference Material is applicable for use in LC/MS or GC/MS testing applications in clinical toxicology forensic analysis workplace drug testing and pharmaceutical research.
Selleck Chemical LLC 3-deazaneplanocin A (DZNeP) HCl 1mg 120964-45-6 NSC 617989 HCl
3-deazaneplanocin A HCl (DZNeP, NSC 617989), an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM in a cell-free assay. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Sigma Aldrich Fine Chemicals Biosciences Lopinavir United States Pharmacopeia (USP) Reference Standard | 192725-17-0 | 350MG
Lopinavir United States Pharmacopeia (USP) Reference Standard | Mol Wt: 628.8 | 192725-17-0 | 350MG